Location: Barcelona - Spain (3 days working from the office and 2 days working from home)

Why the job exists.

• Alexion, Astrazeneca Rare Disease, is expanding its leadership in transformative rare disease therapies beyond complement biology by advancing innovative therapies across metabolic, bone metabolism and endocrine disorders.

• Building on its leadership in hypophosphatasia (HPP) and expanding into conditions such as hypoparathyroidism (HPT), the company with the Eneboparatide asset combines cutting edge sicence with strong value and access strategies to improve outcomes for patients living with rare metabolic and endocrine diseases.

• To achieve above ambition and timely sustainable market access & pricing across our global geography footprint requires to enhance our Global Access-Pricing capabilities to recruit a global Access & Pricing lead for Endocrinology

This is what you will do:

Join a highly valued, strategic team that is fundamental in realizing the potential of our life-changing medicines. It's through our work that AstraZeneca is able to ensure the right access is provided to our transformative medicines.

Alexion Astrazeneca's Rare Disease Global Value Access and Pricing (GVAP) team is seeking a qualified Director to be part of a dynamic and growing team with responsibility for key program (s) with near term new product launches and label expansions.

As a key team member within the GVAP Team you will lead the development and execution of the global value, access and price strategies for Eneboparatide & hypoparathyroidism pipeline to support patient access to our medicines.

This is a strategic role requiring an ability to shape a global value, access and pricing strategy for Eneboparatide & hypoparathyroidism pipeline across the diversity of our US/Japan/ EU key rare diseases markets.

The ideal candidate for this role has an in depth understanding and application of payer's HTA & reimbursement eco-systems for Rare diseases/oncology medicines in US/Japan/ EU key markets as well as a robust experience in developing access, pricing and reimbursement strategies within competitive environment.

You will be responsible for:

Value

• Lead and drive across function development of a clear differentiated Eneboparatide asset value proposition while influencing without authority and navigating complex organizational systems.

• Keep up to date with scientific developments, bringing the latest techniques and analyses to build the strongest possible Eneboparatide asset value proposition in context of rare diseases evidence larger uncertainty and competiiton

• Influence Clinical Development Programs of Endocrinology assets portfolio to ensure that endpoints and evidence generation plans (i.e. clinical, economic, and humanistic outcomes) are incorporated to support optimized patient access & match payer needs. This includes securing timely country input of endpoints and evidence generation plans in priority target countries.

• Provide support to GMMA commercial team to realize asset progress through governance milestones focused on market access potential, evidence, and TPP requirements.

Access

• Lead a cross functional team to drive hypoparathyroidism Global market access and pricing strategies and activities in close partnership with country access representatives.

• Lead the assessment of P&R risks and opportunities & implementation of corresponding mitigation actions specific to Eneboparatide launch & hypoparathyroidism.

• Create and roll out of strategic value, access and pricing communication tools and materials to support local P&R submissions and negotiations such as pricing frameworks, negotiation strategy & toolkits, etc. per the enterprise-wide launch framework.

• Lead development of global reimbursement dossier and overall across function market access readiness hypoparathyroidism plans in close collaboration with target key countries and support global functions (HeoR, medical, commercial),

• Represent GVAP perspective and strategy across various cross-functional teams (including Global Program Teams, Global Launch Teams) and provide updates and guidance to local teams, as necessary.

• Understand & incorporate the patient perspective of the disease and recommend strategies that can support the patient voice in key payer negotiations.

Pricing

• Develop Eneboparatide launch & hypoparathyroidism therapies pricing strategy.

• Conduct payer and value assessments to identify key market specific P&R drivers and barriers to develop differentiated value propositions, inform evidence generation plans, regulatory strategy and development decisions.

• Targeting the top 8 rare diseases markets, Lead and co-create market level P&R strategies and support P&R submissions and negotiations to drive positive outcomes.

• Review P&R cases submitted by markets. Support markets in maintaining value while unlocking local access.

• Offer critical strategic inputs to inform access and pricing assumptions, creating accurate, market-driven LTP assumptions.

• Communicate frequently and effectively with GMMA senior leadership, and other identified stakholders, particularly in relation to Eneboparatide launch & hypoparathyroidism portfolio P&R strategy.

You will need to have:

• Demonstrate leadership and ability to take initiative and consistently deliver high-quality work in the context of rare diseases evidence larger uncertainty and competiton.

• Ability to Communicate effectively and translating science into compelling payer value story benefits to Alexion leadership and other identified stakeholders including close collaboration local market access colleagues and with the Commercial Launch Excellence function.

• Experience working on evidence-based innovative value solutions, e.g. through working with local payers in EU or commercial customers in the US.

• Relevant Graduate degree eg. PhD, PharmD, biomedical science, business, or economics.

• Highly specialized rare disease/oncology market access experience.

• Relevant drug development and/or commercialization experience within the pharmaceutical/medical industry of greater than 6 years.

• Knowledge of the needs and expectations of national and regional payers, insurers, and commercial customers in our strategic markets (US, Japan, top 4 EU). Knowledge and experience in key markets (e.g. DE, IT, SP, FR, UK) are appreciated.

The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Date Posted

27-abr-2026

Closing Date

12-may-2026

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.