Analytical & Formulation Sciences, Protein Formulation Senior Scientist

Almirall
Almirall
SANT FELIU DE LLOBREGATOn-siteCompetitiveAdded 16 days ago

Original Advert

We're building the future of medical dermatology by focusing on unmet patient needs and giving people the space to think independently, take ownership and make an impact that matters.

Our purpose is simple: to transform patients' lives by addressing real needs. We work with care, act with courage, keep things simple and focus our innovation where it makes a difference.

Recognised as a Top Employer in Spain since 2008 and in Germany since 2025, we continue to invest in an environment where people can grow and move forward.

If you care differently, you belong here.

POSITION SUMMARY / MISSION

We are seeking an accomplished Senior Scientist to join our Analytical & Formulation Sciences team, specializing in the design and execution of formulation studies for protein therapeutics and new complex modalities in medical dermatology.

In this role, you will lead efforts to support developability assessment, early formulation development, and high-concentration formulation design for subcutaneous administration. Your expertise will be pivotal in evaluating and optimizing the stability, compatibility, and in-use performance of protein-based products. You will collaborate closely with analytical, process, and CMC teams to guide molecule selection and development, ensuring robust formulation strategies that advance our diverse dermatology portfolio. The ideal candidate will drive innovation in formulation sciences, mentor fellow scientists, and promote cross-functional experimental approaches to address emerging challenges of our diverse medical dermatology portfolio.

CORE RESPONSIBILITIES

  • Design, develop, and evaluate formulations for biologics (proteins, mRNA, complex modalities) across discovery and development stages.

  • Collaborate with CMC teams to ensure phase-appropriate formulation strategies.

  • Act as subject matter expert (SME) in internal technical governance, project reviews, and regulatory discussions, ensuring alignment between formulation approaches and broader CMC objectives.

  • Troubleshoot complex formulation challenges, proposing scientifically sound solutions to advance project objectives.

  • Conduct formulatability, formulability, and developability assessments, integrating physicochemical and biophysical data.

  • Develop high-concentration formulations suitable for subcutaneous administration and patient usability.

  • Perform protein stability studies (accelerated, stress, in-use, and long-term) and excipient compatibility evaluations.

  • Analyze data to establish structure-formulation-stability relationships.

  • Support technology transfer to CDMOs and contribute to technical documentation and regulatory packages.

  • Contribute to innovation initiatives in formulation technology and stability prediction.

  • Mentor junior scientists and help shape laboratory best practices and formulation workflows.

  • Initiate and lead collaborations with internal and external partners on new technologies and disease understanding, accelerating innovation and knowledge sharing.

REQUIRED EDUCATION AND EXPERIENCE

  • PhD in Analytical Chemistry, Biochemistry, or a related scientific discipline.
  • ≥5 years of relevant experience in biopharmaceutical analytical development (industry or academic translational research).
  • Strong understanding of protein stability, biophysical characterization, and formulation science.
  • Familiarity with developability assessments, excipient screening, and in-use stability.
  • Experience in non-GxP research and early development environments preferred.
  • Strong communication and collaboration skills in cross-functional R&D settings.
  • Demonstrated ability to provide scientific leadership and strategic direction in cross-functional settings.
  • Excellent problem-solving, communication, and mentoring skills.
  • Experience interfacing with CMC, Regulatory, and external partners (CDMOs, CROs) desirable.
  • Excellent written and verbal communication skills, with experience presenting at international scientific meetings.

PREFERRED SKILLS & COMPETENCES

  • Hands-on experience with high-concentration formulation and subcutaneous delivery systems.
  • Experience in formulation development for dermatological products is a strong plus.
  • Strong organizational skills and meticulous attention to detail.
  • Exceptional communication and leadership abilities, with a track record of mentoring and team-building.
  • Demonstrated ability to lead technology collaborations and drive scientific innovation.
  • Fluency in spoken and written English is essential, other languages are a plus.

Medical Doctor - Talent Community

Barcelona, Spain
1d ago

Associate Director Global Medical Excellence

Barcelona, Spain
1w ago

Principal Investigator, Project Leader

SANT FELIU DE LLOBREGAT
1w ago

Associate Director, Global Rewards

Barcelona, Spain
1w ago

Medical Writing Senior Manager

SANT FELIU DE LLOBREGAT
1w ago

Commercial Training Senior Manager Healthcare

Barcelona, Spain
1w ago

Compliance Iberia Manager - Temporary

Barcelona, Spain
1w ago

Global Clinical Development Physician

SANT FELIU DE LLOBREGAT
1w ago

Global Medical Operations Manager

Barcelona, Spain
1w ago

Medical Affairs Senior Manager Temporary

Barcelona, Spain
2w ago

IT Business Process Manager

SANT ANDREU DE LA BARCA
2w ago

Associate Director, Safety Physician

SANT FELIU DE LLOBREGAT
3w ago

Inspector/a de Serveis de Neteja Viària i Recollida de Residus (Viladecans)

Spain
€20K1d ago

Groups & Events Executive

Barcelona, Spain
1d ago

Commis Cook

Barcelona, Spain
1d ago

QCM - Certifying Staff Member (Quality Material Services) Seville

Sevilla, Spain
1d ago

Manufacturing Engineering Temporary

Albacete, Spain
1d ago

Portfolio Monitoring Specialist – Real Estate

Madrid, Spain
1d ago

Gestor/a de tráfico

Burgos, Spain
1d ago

FAL A400M Industrial Manager – Cost Management & EAC Control

Sevilla, Spain
2d ago

PMO and Business Support Manager Aerostructures Programmes

Sevilla, Spain
2d ago

Delivery Manager - Evinova

Barcelona, Spain
2d ago

Global Forecasting & Insights Director

Barcelona, Spain
2d ago

Técnico Middleware

Madrid, Spain
2d ago

Principal Investigator, Project Leader

SANT FELIU DE LLOBREGAT
1w ago

Global Clinical Development Physician

SANT FELIU DE LLOBREGAT
1w ago

Medical Writing Senior Manager

SANT FELIU DE LLOBREGAT
1w ago

Associate Director, Safety Physician

SANT FELIU DE LLOBREGAT
3w ago

Cellular Immunologist - TEMPORARY

SANT FELIU DE LLOBREGAT
3w ago

R&D Procurement Trainee

SANT FELIU DE LLOBREGAT
1mo ago

Regulatory Affairs Senior Manager

SANT FELIU DE LLOBREGAT
1mo ago

Analytical & Formulation Sciences, Protein Mass Spectrometry Principal Scientist

SANT FELIU DE LLOBREGAT
1mo ago

Regulatory Affairs Manager

SANT FELIU DE LLOBREGAT
1mo ago

QA Manager

SANT FELIU DE LLOBREGAT
1mo ago

Analytical & Formulation Sciences, Mrna Analysis Trainee

SANT FELIU DE LLOBREGAT
1mo ago

Analytical & Formulation Sciences, Bioassays & Functional Analysis Trainee

SANT FELIU DE LLOBREGAT
1mo ago

Application managed by Almirall