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Senior Software Engineer, AI-Native Development

On-site in Barcelona·Full-time·Added 3 days ago (last checked 15 Oct)

AstraZeneca

32 open roles

Overview

Work mode
On-site, Barcelona
Contract
Full-time
Experience
5+ years

Visa options

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Skills

Requirements

What we're looking for

  • 5+ years of professional software engineering experience shipping production systems.
  • Strong proficiency in at least one backend language (Java, Node.js, or similar) and frontend technologies (TypeScript, React, React Native).
  • Experience building and operating RESTful & GraphQL APIs, with solid understanding of HTTP, JSON, and OpenAPI specifications.
  • Experience with document-based storage (MongoDB or similar) and data streaming technologies (Kafka or similar).
  • Practical, daily experience using AI-assisted development tools in your own coding workflow. You should be able to articulate how AI tools change the way you design, write, test, and review code.
  • Experience building or integrating AI/LLM features into production applications (not just experimentation or prototypes).
  • Proficiency with CI/CD pipelines (GitHub Actions, Azure DevOps, or similar) and containerization (Docker, Kubernetes).
  • Experience with AWS cloud services.
  • Strong testing discipline: unit testing, integration testing, and BDD frameworks (Cucumber or similar).
  • Familiarity with regulated or compliance-sensitive software development environments.

Nice to have

  • Experience building agentic AI systems, including multi-step LLM workflows, tool use, and evaluation/observability for AI features.
  • Experience with clinical trial software, eCOA, medical devices or healthcare/life sciences technology.
  • Familiarity with GxP or SaMD validation processes.
  • Experience designing solutions for complex projects within large organizations. Contributions to open-source projects or visible technical thought leadership.

The role

Are you ready to build AI-native software that accelerates clinical trials and improves patient outcomes? Do you thrive in a full-stack environment where AI is a core tool, not an add-on? Join us in Barcelona to design and deliver products that power the next generation of clinical research.

In this role, you will write production code daily and take end-to-end ownership of what you ship. You will design and implement robust backend services, contribute to modern frontend experiences, and integrate AI capabilities directly into our product suite. Your work will help simplify participation in clinical trials for patients and professionals, making a measurable difference in how life-changing therapies reach those who need them.

You will also help define how engineering teams build with AI: setting conventions for AI-assisted development, establishing prompt engineering patterns, and creating quality gates for AI-generated code. Your impact will be felt immediately in product delivery and over time in the standards and practices that shape our AI-native engineering culture.

What you'll do

Accountabilities

  • Full-Stack Product Delivery: Write clean, well-tested, production-ready code across backend and frontend, owning outcomes from design through deployment and monitoring to deliver features that power clinical trials at scale.
  • AI-Native Development: Design and implement LLM-powered workflows, intelligent automation, and AI-driven user experiences; develop prompt engineering patterns, evaluation frameworks, and testing strategies; and apply critical judgment to all AI-generated code.
  • Backend and APIs: Build scalable backend and BFF services, RESTful and GraphQL APIs, and data streaming pipelines that meet reliability, performance, and compliance needs.
  • Frontend Experience: Contribute to React and React Native applications when full-stack ownership is required, ensuring cohesive, high-quality user experiences.
  • Reliability and Observability: Troubleshoot complex production issues, perform root cause analysis, and implement preventive improvements; enhance monitoring and resilience to protect service levels.
  • Platform and DevOps Partnership: Collaborate on infrastructure-as-code, CI/CD pipelines, automated deployment and recovery, and container orchestration for speed and stability.
  • Secure and Compliant Engineering: Operate effectively in regulated environments, applying disciplined engineering practices and evidence generation to meet validation expectations.
  • Collaboration and Mentorship: Elevate team standards through substantive code reviews; mentor peers in AI-assisted development and modern workflows; contribute to agile planning, estimation, and retrospectives.
  • Progression and Impact: Deliver immediate value in features and platform capabilities, then expand your influence by shaping AI-first engineering practices and reusable components that accelerate multiple product teams.

How you'll work

This is an in-office role based in Barcelona, ES, with a requirement to work a minimum of three days per week on-site. Remote or travel flexibility is not available.

Date Posted

13-oct-2026

Closing Date

28-dic-2026

Hiring process

2 steps1 interviewa task to do
  1. Application

  2. Recruiter contact · With a recruiter

  3. Assessment

    Not every role

    Some roles, especially graduate roles, add a game-based assessment, a video or telephone interview, or an assessment day.

  4. Interview

    A two-way conversation about your skills and suitability for the role, and a chance for you to find out if AstraZeneca is right for you.

  5. Pre-employment screening

  6. Offer

  • Candidates who reach interview stage or beyond usually get feedback within 14 days of the role's closing date.
  • Interview travel expenses are reimbursed for journeys over 100km.
  • Alcohol and drug testing is carried out for new hires where required by local country legislation.

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company that discovers, develops, and commercializes prescription medicines in therapeutic areas including oncology, cardiovascular, renal and metabolism, and respiratory and immunology. With a workforce of over 80,000 employees worldwide, the company is headquartered in Cambridge, UK, and operates across more than 100 countries, focusing on innovative medicines and advanced technologies like AI and data science to transform patient care.

In Spain, AstraZeneca has a significant presence with offices in Madrid and Barcelona, contributing to clinical development, regulatory affairs, and commercial operations. The company is known for its collaborative and inclusive culture, offering international professionals opportunities to work on global projects, particularly in areas like cell therapy, AI-driven health solutions (Evinova), and patient safety. With a strong commitment to diversity and innovation, AstraZeneca Spain is an attractive destination for talent seeking to make a global impact while living in Spain.

Industry
Pharma
Founded
1999
Employees
10,000+
Headquarters
Cambridge, UK
In Spain
Madrid, Barcelona

Good to know if you are moving

  • AstraZeneca offers a global, multicultural work environment with opportunities to collaborate with colleagues across the world.
  • The company has a strong commitment to employee development and offers various career growth programs.
  • Spain offices are located in major cities like Madrid and Barcelona, offering a high quality of life and vibrant culture.
  • AstraZeneca is a leader in innovative therapies, providing employees with the chance to work on cutting-edge medical advancements.
  • The company supports flexible working arrangements and promotes a healthy work-life balance.

In their own words

Additional information

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

All open roles at AstraZeneca

Location

AstraZeneca · Barcelona

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