Postdoctoral Researcher in Centrosome Proteostasis and Cell Biology

The Cell Division and Organelle Biology lab is recruiting a highly motivated postdoctoral researcher to investigate how centrioles and centrosomes maintain their structural integrity throughout the cell cycle. The successful candidate will contribute to the CENTROSTASIS project, focusing on the turnover of centrosomal proteins and the molecular pathways that regulate organelle maintenance. The role combines quantitative proteomics, cell-based assays and advanced microscopy to uncover fundamental mechanisms of proteostasis and their relevance to health and disease.

The Bettencourt-Dias Lab investigates cell division and organelle biology, with particular emphasis on centrosomes and cilia. The team uses cell biology, high-resolution microscopy, proteomics and molecular approaches to understand how centrioles are assembled, maintained and eliminated in heath and disease, and how these processes evolved in eukaryotes.

• Develop and apply experimental approaches to measure turnover of centrosome components and their dynamics across the cell cycle.
• Contribute to centrosome enrichment and quantitative proteomics workflows in collaboration with CRG core facilities.
• Investigate regulators of protein turnover and centriole integrity using molecular perturbations and biochemical and imaging assays.

• Contract duration: Technical and scientific activities contract linked to the project (estimated duration 3 years)
• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
• Target start date: December 2026.

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

• Highly developed organizational skills
• Careful experiment planning, and rigor in scientific pursuits
• Capacity to work in a highly collaborative environment
• Great communication skills of your scientific results